Browsing Department of Pharmaceutical Sciences and Biotechnology by Subject "Acetylcholinesterase"

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    • Novel isosorbide di-ester compounds as inhibitors of acetylcholinesterase. 

      Carolan, Ciaran G.; Gaynor, Joanne M.; Dillon, Gerry P.; Khan, Denise; Ryder, Sheila A.; Reidy, Sean; Gilmer, John F. (Elsevier, 2008-09-25)
      We report herein that a variety of isosorbide di-esters, previously reported to be novel substrates for butyrylcholinesterase (BuChE, EC 3.1.1.8), are in fact inhibitors of the homologous enzyme acetylcholinesterase (AChE), ...