Research, Innovation & Enterprise: Recent submissions
Now showing items 101-120 of 494
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Monitoring in vitro extracellular matrix protein conformations in the presence of biomimetic bone-regeneration scaffolds using functionalized gold-edge-triangular silver nanoparticles
(MDPI, 2022-12-23): In the cellular environment, high noise levels, such as fluctuations in biochemical reactions, protein variability, molecular diffusion, cell-to-cell contact, and pH, can both mediate and interfere with cellular ... -
The design, development, and testing of novel next generation in vitro agar-based urethral models for medical device innovation
(Technological University of the Shannon: Midlands Midwest, 2022-04)Catheters are one of the most utilised medical devices in modern medicine with catheter associated urinary tract infections (CAUTI) being ubiquitous in worldwide healthcare settings. These infections negatively affect ... -
Enhancing drug solubility through advanced polymer extruded shellac-based matrix drug delivery systems
(Technological University of the Shannon: Midlands Midwest, 2022-09)The main objective of this study is to enhance the solubility of the model drug fenofibrate, by forming amorphous solid dispersions using a hot melt extrusion process. Hot melt extrusion offers an efficient way of ... -
A risk assessment-based control strategy to formulate a potent, efficacious, and non-invasive topical onychomycotic dosage form
(Technological University of the Shannon: Midlands Midwest, 2021)This project involves the development of a strategy to formulate a novel dosage form with modified coconut oil (MCO) as the active pharmaceutical ingredient to treat onychomycosis caused by T. rubrum and C. albicans. ... -
Big data testing techniques: taxonomy, challenges and future trends
(Tech Science Press, 2022-10-31)Big Data is reforming many industrial domains by providing decision support through analyzing large data volumes. Big Data testing aims to ensure that Big Data systems run smoothly and error-free while maintaining the ... -
A study of network intrusion detection systems using artificial intelligence/machine learning
(MDPI, 2022-11-18)The rapid growth of the Internet and communications has resulted in a huge increase in transmitted data. These data are coveted by attackers and they continuously create novel attacks to steal or corrupt these data. The ... -
Roles of medicinal mushrooms as natural food dyes and dye-sensitised solar cells (DSSC): synergy of zero hunger and affordable energy for sustainable development
(MDPI, 2022)In 2015, approximately 195 countries agreed with the United Nations that by 2030, they would work to make the world a better place. There would be synergies in accomplishing the 17 Sustainable Development Goals (SDGs). ... -
Synthesis, properties, and applications of polylactic acid-based polymers
(Wiley, 2022-11-03)Polylactic acid (PLA) is known as one of the greatest promising bioabsorbable and compostable polyesters with the capability of high molecular weight synthesis. Lactic acid condensation, azeotropic dehydration, and ... -
Geobacillus stearothermophilus and Bacillus atrophaeus spores exhibit linear inactivation kinetic performance when treated with an industrial scale vaporized hydrogen peroxide (VH2O2) sterilization process
(Wiley, 2022)Many medical devices are supplied as sterile for safe patient care (McEvoy and Rowan 2019). The global sterilization services market is projected to reach USD 5.5 billion by 2026, growing at a compound annual growth rate ... -
Enhanced antimicrobial activity of biocompatible bacterial cellulose films via dual synergistic action of curcumin and triangular silver nanoplates
(2022-10-13)Curcumin and triangular silver nanoplates (TSNP)-incorporated bacterial cellulose (BC) films present an ideal antimicrobial material for biomedical applications as they afford a complete set of requirements, including a ... -
Bioresorbable chitosan-based bone regeneration scaffold using various bioceramics and the alteration of photoinitiator concentration in an extended UV photocrosslinking reaction in an extended UV photocrosslinking reaction
(MDPI, 2022-10-28)Bone tissue engineering (BTE) is an ongoing field of research based on clinical needs to treat delayed and non-union long bone fractures. An ideal tissue engineering scaffold should have a biodegradability property ... -
Formulation and evaluation of Fenbendazole extended-release extrudes processed by hot-melt extrusion
(MDPI, 2022-10-06)This study aimed to demonstrate the feasibility of hot-melt extrusion in the development of extended-release formulations of Fenbendazole (Fen) dispersed in PEO/PCL blend-based matrices. Their thermal, physical, chemical ... -
Process optimization for the 3D printing of PLA and HNT composites with Arburg plastic freeforming
(MDPI, 2022-10-12)The industrial use of additive manufacturing continues to rapidly increase as new technology developments become available. The Arburg plastic freeforming (APF) process is designed to utilize standard polymeric granules ... -
Heat dissipation plays critical role for longevity of polymer-based 3D-printed inserts for plastics injection moulding.
(MDPI, 2022-10-08)Injection moulding is a polymer processing method of choice for making plastic parts on industrial scale, but its traditional mould is made from tooling steel with time-consuming and costly production. Additive manufacturing ... -
Ganodiesel: a new biodiesel feedstock from biomass of the mushroom Ganoderma lucidum
(MDPI, 2022-08-29)There is a pressing demand for new sustainable eco-friendly approaches to producing green energy worldwide. This study represents the novel production of biodiesel feedstock from the medicinal mushroom Ganoderma lucidum ... -
Development of the large-tonnage pressure-type prestressed anchor cable with BFRP for geotechnical engineering and its mechanical properties
(Wiley/Hindawi, 2022)Prestressed anchor cable is widely used in geotechnical engineering to control the displacement or landslide of an unstable slope. However, the traditional cable anchor is made of steel material, which is easy to get rust ... -
Hyaluronic acid: a review of the drug delivery capabilities of this naturally occurring polysaccharide
(MDPI, 2022-08-23)The inclusion of physiologically active molecules into a naturally occurring polymer matrix can improve the degradation, absorption, and release profile of the drug, thus boosting the therapeutic impact and potentially ... -
Effectiveness of front line and emerging fungal disease prevention and control interventions and opportunities to address appropriate eco-sustainable solutions
(Elsevier, 2022-08-21)Fungal pathogens contribute to significant disease burden globally; however, the fact that fungi are eukaryotes has greatly complicated their role in fungal-mediated infections and alleviation. Antifungal drugs are often ... -
The role of digital technologies in supporting and improving fishery and aquaculture across the supply chain - quo vadis?
(Elsevier, 2022-07-12)Fish constitute important high protein products to meet the demands of an increasing global population. However, the continued depletion of wild fish stocks is leading to increased strain on the aquaculture sector in terms ... -
SoK: context and risk aware access control for zero trust systems
(Wiley/Hindawi, 2022-06-30)Evolving computing technologies such as cloud, edge computing, and the Internet of )ings (IoT) are creating a more complex, dispersed, and dynamic enterprise operational environment. New security enterprise architectures ...
