PRISM: Polymer, Recycling, Industrial, Sustainability and Manufacturing Institute (Midlands): Recent submissions
Now showing items 181-200 of 240
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Additive manufacturing of PLA/HNT nanocomposites for biomedical applications
(Elsevier, 2019)Additive manufacturing has been of great interest of research in various applications due to their ease in processability, cost effectiveness and adaptability. In this study Poly Lactic Acid (PLA) was used as the base ... -
Processing stability and the significance of variation in extrusion speeds and temperture on SSB® 55 Pharma Grade Shellac for Oral Drug Delivery
(MDPI, 2017-09-06)The melt-extrusion process is utilized in the pharmaceutical arena for the manufacturing of a variety of dosage forms and formulations, including solid dispersions. This technology is considered an efficient and continuous ... -
Nanofillers can be used to enhance the thermal conductivity of commercially available SLA resins.
(Elsevier, 2019-06)Stereolithography (SLA) is a form of 3D printing technology used for the production parts and patterns in a layer by layer fashion. Traditionally, 3D printing has been used for the manufacture of prototypes, however it is ... -
Optimizing the hardness of SLA printed objects by using the neural netwok and genetic algorithm
(Elsevier, 2019-06)In the developing field of manufacturing, 3D printing is rapidly increasing the horizon of what is possible. However, the possibility of implementing new 3D methods of production has brought new challenges for industries, ... -
Enhancing the bioavailability of hydrophobic drugs using hot melt extrusion
(Athlone Institute of Technology, 2018-04-24)Many existing drugs (as well as new revelations) in the pharmaceutical industry bear a distinct disadvantage in the sense that they are not water soluble, displaying low bioavailability values and consequently a reduced ... -
3D printed end of arm tooling (EOAT) of a robotic arm
(Athlone Institute of Technology, 2018-04-24)This research furthers the practice of designing and manufacturing an EOAT for low weight applications by utilising additive manufacturing (“3D Printing”) techniques to decrease energy consumption via tool weight savings ... -
Degradable nanocomposites for fused filament fabrication applications.
(MDPI, 2018-05-09)There has been a substantial increase in the use and development of plastics over the last century. However, due to ever-diminishing petroleum feedstocks and growing concern for the environment, there has been a rise in ... -
Material considerations for fused-filament fabrication of solid dosage forms.
(MDPI, 2018-04-02)Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ... -
Additive manufacturing of personalized pharmaceutical dosage forms via stereolithography.
(MDPI, 2019-12-03)The introduction of three-dimensional printing (3DP) has created exciting possibilities for the fabrication of dosage forms, paving the way for personalized medicine. In this study, oral dosage forms of two drug ... -
The influence of mechanical stretching and freeze-thaw processing on the properties of polyvinyl alcohol hydrogels for drug delivery applications
(Athlone Institute of Technology, 2018-04-24)The study describes the development of physically cross-linked polyvinyl alcohol (PVA) hydrogels using uniaxial orientation via freeze-thawing (F/T). Although cryogels have shown significant improvements in long-term ... -
Pathogen displacement during intermittent catheter insertion: a novel in vitro urethra model.
(Wiley, 2019-11-29)Aim: To develop a novel in vitro urethra model and use it to determine if insertion of an intermittent urinary catheter (IC) displaces pathogenic bacteria from the urethral meatus along the urethra. Methods: Displacement ... -
Smart hydrogels: therapeutic advancements in hydrogel technology for smart drug delivery applications.
(Wiley, 2015-12)Hydrogels are a fusion of solid and liquid phases which closely mimic biological tissue. As such they have enormous potential for drug delivery systems as they are biocompatible and may be tailored to specific applications. ... -
Mechanical properties of anodic titanium films containing ions of Ca and P submitted to heat and hydrothermal treatment.
(Elsevier, 2016-12)Anodic oxidation is a technique widely used to improve the bioactivity of Ti surface. In this study, micro-arc oxidation (MAO) was used to obtain an anodic film incorporating Ca and P ions to evaluate the effect of heat ... -
Synthesis and in vivo behaviour of PVP/CMC/Agar hydrogel membranes impregnated with silver nanoparticles for wound healing applications.
(ACS, 2018)The field of wound healing has seen an increase in research activity in wound care and hydrogel-based dressings have been targeted as a solution for these applications. Hydrogels with silver nanoparticles can present many ... -
Development of high strength nanocomposite for biodegradable stents
(Athlone Institute of Technology, 2018-04-24)The use of biodegradable polymer materials are considered to be good alternatives in urology (Donohue et. al. 2018), cardiovascular (Brie et. al. 2016) and tracheal airway stenosis which provide support before it is absorbed ... -
Degradable polymer nanocomposites for fused filament fabrication applications
(Athlone Institute of Technology, 2018-04-24)The use of plastics in everyday life has increased dramatically during the course of the 20th and 21st century which is primarily due to the characteristics plastics offer in the development of new products to meet the ... -
Synthesis and in vivo evaluation of a scaffold containing wollastonite/β‐TCP for bone repair in a rabbit tibial defect model.
(Wiley Online Library, 2019-08-08)Scaffolds are models designed to aid the interaction between cells and extracellular bone matrix, providing structural support for newly formed bone tissue. In this work, wollastonite with β‐TCP porous ceramic scaffolds ... -
The development of a melt-extruded shellac carrier for the targeted delivery of probiotics to the colon.
(MDPI, 2017-12)Hot melt extrusion (HME) is considered an efficient technique in developing solid molecular dispersions, and has been demonstrated to provide sustained, modified and targeted drug delivery resulting in improved ... -
Influence of annealing and biaxial expansion on the properties of Poly-l-lactic) medical tubing.
(MDPI, 2019-07-11)Poly-l-lactic acid (PLLA) is one of the most common bioabsorbable materials in the medical device field. However, its use in load-bearing applications is limited due to its inferior mechanical properties when compared ... -
The influence of low shear microbore extrusion on the properties of high molecular weight poly(l-lactic acid) for medical tubing applications.
(MDPI, 2019-04)Biodegradable polymers play a crucial role in the medical device field, with a broad range of applications such as suturing, drug delivery, tissue engineering, sca olding, orthopaedics, and fixation devices. Poly-l-lactic ...
