Now showing items 41-48 of 48

    • Enhancing the bioavailability of hydrophobic drugs using hot melt extrusion 

      Devine, Declan M.; Higginbotham, Clement; Geever, Luke M.; Coffey, Conor (Athlone Institute of Technology, 2018-04-24)
      Many existing drugs (as well as new revelations) in the pharmaceutical industry bear a distinct disadvantage in the sense that they are not water soluble, displaying low bioavailability values and consequently a reduced ...
    • 3D printed end of arm tooling (EOAT) of a robotic arm 

      Ong U Jing, Daniel; Lyons, Sean; Devine, Declan (Athlone Institute of Technology, 2018-04-24)
      This research furthers the practice of designing and manufacturing an EOAT for low weight applications by utilising additive manufacturing (“3D Printing”) techniques to decrease energy consumption via tool weight savings ...
    • The influence of mechanical stretching and freeze-thaw processing on the properties of polyvinyl alcohol hydrogels for drug delivery applications 

      Chee, Bor Shin; De Lima, Gabriel G.; Devine, Declan M.; Nugent, Michael J.D. (Athlone Institute of Technology, 2018-04-24)
      The study describes the development of physically cross-linked polyvinyl alcohol (PVA) hydrogels using uniaxial orientation via freeze-thawing (F/T). Although cryogels have shown significant improvements in long-term ...
    • Smart hydrogels: therapeutic advancements in hydrogel technology for smart drug delivery applications. 

      de Lima, Gabriel Goetten; Kanwar, Diwakar; Macken, Derek; Geever, Luke; Devine, Declan M.; Nugent, Michael J.D. (Wiley, 2015-12)
      Hydrogels are a fusion of solid and liquid phases which closely mimic biological tissue. As such they have enormous potential for drug delivery systems as they are biocompatible and may be tailored to specific applications. ...
    • Development of high strength nanocomposite for biodegradable stents 

      Venkatesh, Chaitra; Chen, Yuanyuan; Cao, Zhi; Brennan, Shane; Major, Ian; Lyons, John G.; Devine, Declan M. (Athlone Institute of Technology, 2018-04-24)
      The use of biodegradable polymer materials are considered to be good alternatives in urology (Donohue et. al. 2018), cardiovascular (Brie et. al. 2016) and tracheal airway stenosis which provide support before it is absorbed ...
    • Degradable polymer nanocomposites for fused filament fabrication applications 

      Healy, Andrew V.; Geever, Luke M.; Devine, Declan M.; Lyons, John G. (Athlone Institute of Technology, 2018-04-24)
      The use of plastics in everyday life has increased dramatically during the course of the 20th and 21st century which is primarily due to the characteristics plastics offer in the development of new products to meet the ...
    • Electrospun hydrogels composites for bone tissue engineering. 

      Chee, Bor Shin; de Lima, Gabriel Goetten; Devine, Declan; Nugent, Michael J. D. (Woodhead Publishing, 2019)
      Electrospinning is one of the foremost nanotechnology applications to fabricate bone tissue engineering scaffolds with sizes in the nanometer range. It is regarded as a versatile, inexpensive, and relatively simple methodology ...
    • Oriented polymeric sheets exhibiting dichroism and articles containing the same. 

      Kumar, Anil; Foller, Peter C.; Park, David; Devine, Declan; Bastiaansen, C.W.M.; Tennissen, J.P.; Cloonan, Martin; Higginbotham, Clement L. (2007-12-20)
      Provided is an oriented polymeric sheet comprising a photochromic-dichroic material, wherein the sheet exhibits dichroism in an activated state. Also provided is a multilayer composite comprising at least a support layer ...