The preparation of nanocomposite scaffolds for use in bone tissue engineering.

Abstract

Bone is the second most frequently transplanted tissue in humans. There are 2.2 million bone graft procedures annually, which have several disadvantages such as: donor site morbidity, risk of disease transmission and a limited supply of bone. While several bone substitute materials exist, none fulfil all the requirements of an ideal bone substitute material, which should mimic as closely as possible natural bone. Therefore, the aim of this study was to develop a multifunctional nanocomposite scaffold for use in bone tissue engineering which prevents antimicrobial attachment.