Atlantic Techological University (Sligo): Recent submissions
Now showing items 61-80 of 392
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A review of chromatography methods for the large scale downstream protein purification of monoclonal antibodies /
(Institute of Technology, Sligo, 2019)Researchers have continually proposed new non-chromatographic methods for manufacturing biopharmaceutical products. However, this report will show that chromatography remains the backbone of the downstream operation. ... -
An alternative to Triton X-100 for use in viral inactivation for recombinant factor VIII /
(Institute of Technology, Sligo, 2019)Solvent detergent combinations for viral inactivation have long been used in the manufacture of Biopharmaceutical products due their proven safety record for inactivating viruses. Triton X-100, a non-ionic detergent, has ... -
Distributed micro-control and demand side management in district heated systems /
(Institute of Technology, Sligo, 2013) -
European Clinical Trial Medical Device Regulation and the Protection of Human Participants /
(Institute of Technology, Sligo, 2018)The focus of this research is in the area of European clinical trial regulation for medical devices to determine if the health and welfare of human participants is protected. There were four questions to be addressed: 1) ... -
Getting to the core of the matter : an exploratory study on how social enterprises in the West of Ireland identify their potential target market and communicate their core brand values /
(Institute of Technology, Sligo, 2017)The Social Enterprise Sector has grown rapidly in many countries in recent years to fill the gaps in social services. It helps to increase employment and solve public problems, thus promoting work integration and the ... -
Investigation of the mineral profile of Fucus serratus Linneaus aqueous extracts and examination of the routes of uptake of minerals both in vivo and in vitro /
(Institute of Technology, Sligo, 2018)Seaweed baths are used to promote health and well-being. Seaweed typically contains water, fibre, carbohydrate, protein, lipid, vitamins and minerals. Minerals can account for up to 40% of its composition. Iodine is vital ... -
Unilateral strength training and mirror therapy for enhancing upper limb motor function post stroke /
(Institute of Technology, Sligo, 2019)Cross-education of strength appears to be beneficial in the rehabilitation of injuries and illnesses causing bilateral asymmetry. Furthermore, evidence for the effectiveness of mirror therapy to enhance cross-education in ... -
Unilateral strength training and mirror therapy for enhancing lower limb motor function after stroke /
(Institute of Technology, Sligo, 2019)Stroke is the leading cause of adult disability. Hemiparesis and spasticity are common impairments, resulting in ankle dorsiflexion dysfunction and gait asymmetry. Often the most-affected side is too weak to engage in ... -
Multiregional Medical Device Registration /
(Institute of Technology, Sligo, 2017)The landscape of multiregional medical device registration is an area with highly variable regulations, varying regulator application and expectations, alongside swift changes in some regions. Accessing international ... -
Ultra high performance fibre reinforced concrete for infrastructure construction /
(Institute of Technology, Sligo, 2019 gradu) -
An in vitro investigation into the anti-cancer potential of novel tetraoxane compounds for the treatment of chronic lymphocytic leukaemia /
(Institute of Technology, Sligo, 2018)This study aims to evaluate the therapeutic potential of five novel tetraoxane compounds and one novel tetraoxane-naphthalimide hybrid compound for chronic lymphocytic leukaemia. These novel compounds are predicted to ... -
An experimental investigation of helical piles subject to inclined pullout loads /
(Institute of Technology, Sligo, 2017) -
An investigation into the compatibility and effectiveness of linking Brazilian carbon mitigation and trading strategies with the EU ETS (European Union Emissions Trading Scheme) /
(Institute of Technology, Sligo, 2018)International climate negotiations have recently underlined the relevance of international cooperation via carbon pricing, as well as the need for support from developed and developing countries to tackle climate change. ... -
Plethora of Potential Platforms: a review of current and future trends in expression system choice in the biopharmaceutical industry /
(Institute of Technology, Sligo, 2018)In the thirty years since the first biopharmaceuticals were approved for use in humans, the choice of expression system for new biopharmaceuticals has remained largely unchanged and is still mainly determined by the necessity ... -
A Review of recently Approved Orphan Designation Biological Drugs /
(Institute of Technology, Sligo, 2018)Orphan Drugs are a critical resource for those suffering from rare diseases and there is an urgent need for many new drugs to address the thousands of serious rare conditions which affect millions of people across the ... -
A Structured Analysis of the Novel Technologies used to alleviate bottlenecks in Biopharmaceutical Manufacturing /
(Institute of Technology, Sligo, 2018)Biopharmaceutical companies are under increasing pressure to meet the market demand from patients. Despite a high growth sector within the life sciences sector, the same types of manufacturing methods have been employed ... -
How do small local food producers build and maintain brand loyalty? /
(Institute of Technology, Sligo, 2017)The objective of this particular study is to investigate how small local food producers build and maintain brand loyalty. Brand loyalty is extremely important for producers to gain market share. It is imperative that they ... -
An exploratory study of the use of social media marketing in the pay TV industry in Ireland /
(Institute of Technology, Sligo, 2017)This research is an exploratory study, which analyses the use of social media by Irish pay-television providers when marketing their services. The main objective of this research is to determine has the use of social ... -
An investigation to determine if there a link between CSR practices and customer loyalty : a case study on Coca-Cola comparing Irish and Spanish consumers /
(Institute of Technology, Sligo, 2017)The purpose of this research is to achieve a deeper understanding of the link between Coca-Cola’s CSR practices and its Irish and Spanish consumers loyalty. The study aims to compare and contrast Irish Coca-Cola consumers ... -
Microalgal phycoremediation of landfill leachate /
(Institute of Technology, Sligo, 2017)The aim of this project was to explore the use of microalgae in remediation of landfill leachate. The isolation of microalgae strains tolerant to a combination of high dissolved salts and ammonia concentrations (typical ...
