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"My heart, your heart"; hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded drug delivery system

dc.contributor.authorYan, Guangming
dc.contributor.authorCao, Zhi
dc.contributor.authorDevine, Declan
dc.contributor.authorGatley, Noel
dc.date.accessioned2020-11-24T11:08:32Z
dc.date.available2020-11-24T11:08:32Z
dc.date.copyright2020
dc.date.issued2020-06
dc.identifier.citationYan, G., Cao. Z., Devine, D., Gately, N. (2020). "My heart, your heart"; hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded drug delivery system. Presented at AIT Poster Presentation Seminar June 2020en_US
dc.identifier.urihttp://research.thea.ie/handle/20.500.12065/3495
dc.description.abstractCardiovascular diseases (CVDs) are the number 1 cause of death globally. Fenofibrate has been shown an excellent treating effect on CVDs. However, Fenofibrate is a neutral, lipophilic compound that is practically insoluble in water, making it challenging to achieve therapeutic levels consistently. As a result, this project was using shellac material as the polymeric matrix to enhance the solubility of Fenofibrate by producing solid dispersion by hot melt extrusion.en_US
dc.formatPDFen_US
dc.language.isoengen_US
dc.publisherAthlone Institute of Technologyen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectHot-melt extrusionen_US
dc.subjectDrug delivery systemsen_US
dc.subjectDrug deliveryen_US
dc.subjectCardiovascular diseasesen_US
dc.subjectSolid dispersionen_US
dc.title"My heart, your heart"; hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded drug delivery systemen_US
dc.typeinfo:eu-repo/semantics/otheren_US
dc.contributor.affiliationAthlone Institute of Technologyen_US
dc.contributor.sponsorIrish Research Councilen_US
dc.identifier.orcidhttps://orcid.org/0000-0003-2765-682Xen_US
dc.identifier.orcidhttps://orcid.org/0000-0002-6638-8920en_US
dc.identifier.orcidhttps://orcid.org/0000-0002-1364-5583en_US
dc.identifier.orcidhttps://orcid.org/0000-0002-2610-2975en_US
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessen_US
dc.subject.departmentMaterials Research Institute AITen_US
dc.type.versioninfo:eu-repo/semantics/publishedVersionen_US


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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International