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Hyaluronic acid: a review of the drug delivery capabilities of this naturally occurring polysaccharide

dc.contributor.authorBuckley, Ciara
dc.contributor.authorMurphy, Emma J.
dc.contributor.authorMontgomery, Therese R.
dc.contributor.authorMajor, Ian
dc.date.accessioned2022-10-10T10:16:55Z
dc.date.available2022-10-10T10:16:55Z
dc.date.copyright2022
dc.date.issued2022-08-23
dc.identifier.citationBuckley, C., Murphy, E.J., Montgomery, T.R., Major, I. (2022). Hyaluronic acid: a review of the drug delivery capabilities of this naturally occurring polysaccharide. Polymers. 14:3442. https://doi.org/10.3390/polym14173442en_US
dc.identifier.urihttp://research.thea.ie/handle/20.500.12065/4067
dc.description.abstractThe inclusion of physiologically active molecules into a naturally occurring polymer matrix can improve the degradation, absorption, and release profile of the drug, thus boosting the therapeutic impact and potentially even reducing the frequency of administration. The human body produces significant amounts of polysaccharide hyaluronic acid, which boasts exceptional biocompatibility, biodegradability, and one-of-a-kind physicochemical features. In this review, we will examine the clinical trials currently utilizing hyaluronic acid and address the bright future of this versatile polymer, as well as summarize the numerous applications of hyaluronic acid in drug delivery and immunomodulation.en_US
dc.formatPDFen_US
dc.language.isoengen_US
dc.publisherMDPIen_US
dc.relation.ispartofPolymersen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectNaturally-occurring polymersen_US
dc.subjectPolysaccharideen_US
dc.subjectImmunotherapiesen_US
dc.subjectBioactivesen_US
dc.subjectHeterpolysaccharidesen_US
dc.subjectDrug-deliveryen_US
dc.titleHyaluronic acid: a review of the drug delivery capabilities of this naturally occurring polysaccharideen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.contributor.affiliationTechnological University of the Shannon Midlands Midwesten_US
dc.contributor.sponsorIrish Research Council, Government of Ireland Postgraduate Scholarship.en_US
dc.description.peerreviewyesen_US
dc.identifier.doi10.3390/polym14173442en_US
dc.identifier.eissn2073-4360
dc.identifier.orcidhttps://orcid.org/0000-0001-9843-340Xen_US
dc.identifier.orcidhttps://orcid.org/0000-0002-5620-0058en_US
dc.identifier.orcidhttps://orcid.org/0000-0003-2749-5376en_US
dc.identifier.orcidhttps://orcid.org/0000-0002-0538-9786en_US
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessen_US
dc.subject.departmentMaterials Research Institute TUS:MMen_US
dc.type.versioninfo:eu-repo/semantics/publishedVersionen_US


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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International