Department of Pharmaceutical Sciences and Biotechnology: Recent submissions
Now showing items 41-60 of 71
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A laboratory investigation of the antimicrobial activity of a selection of western phytomedicinal tinctures.
(Elsevier, 2018-04)Introduction: Following the observed success of a herbal cocktail in controlling and eliminating acute respiratory infections in a group of approximately sixty, 1–3 year old equines, it was decided to test ten of the herbs ... -
Characterisation and toxicological evaluation of hydrogel-type polymeric biomatrials pre-and poststerilisation with a novel pulsed plasma gas-discharge system.
(Athlone Institute of Technology, 2010)This study investigated the in vitro biocompatibility and important physicochemical properties of unique N-vinyl-2-pyrrolidone–acrylic acid based copolymer hydrogels intended for use in biomedical applications. Moreover, ... -
Microbiological degradation of pesticides in yard waste composting.
(American Society for Microbiology, 1991)Changes in public opinion and legislation have led to the general recognition that solid waste treatment practices must be changed. Solid-waste disposal by landfill is becoming increasingly expensive and regulated and no ... -
Fluorinated phenmetrazine “legal highs” act as substrates for high-affinity monoamine transporters of the SLC6 family.
(Elsevier, 2018-05-15)A variety of new psychoactive substances (NPS) are appearing in recreational drug markets worldwide. NPS are compounds that target various receptors and transporters in the central nervous system to achieve their ... -
An investigation into the effectiveness of latent myofascial trigger point dry needling on muscle activation patterns.
(Athlone Institute of Technology, 2016-06)Background: Recent research on latent trigger points (LTrP) provides an opportunity to investigate the efficacy of trigger point (TrP) treatments without pain influencing results. One proposed negative outcome of LTrPs is ... -
Natural and synthetic isothiocyanates possess anticancer potential against liver and prostate cancer in vitro.
(International Institute of Anticancer Research, 2019-07)Background/Aim: Isothiocyanates (ITCs) are phytochemicals with potential cancer-preventative properties derived from the breakdown of glucosinolates that exist in cruciferous vegetables. Studies, to date, have ... -
Isocractic LC methods for the trace analysis of phthalates and 4-nonylphenol in varying types of landfill and adjacent run-offs.
(Taylor & Francis Online, 2007-07)To determine the levels of known endocrine disrupting chemicals such as phthalates and alkylphenols in environmental samples such as leachate water and sediment, suitable isocratic high performance liquid chromatographic ... -
Accelerated solvent based extraction and enrichment of selected plasticisers and 4-nonylphenol, and extraction of tin from organotin sources in sediments, sludges and leachate soils.
(Elsevier, 2009-02-23)Enrichment techniques have become an important feature in the trace analysis of oestrogen mimicking chemicals in the environment. Recent developments such as accelerated solvent extraction (ASE) have improved extraction ... -
Advanced therapies and the outer limits of DNA regulation: new horizons for patents or a scaffold too far?
(Oxford Academic, 2008-04)This Regulation seeks to regulate existing and future advanced therapy medicinal products intended for the market in Member States, being either prepared industrially or manufactured by a method involving an industrial ... -
Investigations on the efficacy of routinely used phenotypic methods compared to genotypic approaches for the identification of staphylococcal species isolated from companion animals in Irish veterinary hospitals
(BMC, 2013)BACKGROUND: Identification of Staphylococci to species level in veterinary microbiology is important to inform therapeutic intervention and management. We report on the efficacy of three routinely used commercial phenotypic ... -
UPLC® method development and validation for the assay of the photolabile drug nifedipine and its trace level degradation products.
(The Institute of Chemistry of Ireland, 2017-06)Quality assurance regulations require that pharmaceutical drugs are highly pure. This is in order to ensure the safety and efficacy of medicines for patients, two fundamental issues of importance in treatment. The safety ... -
Characterisation of biopharmaceuticals
(The Institute of Chemistry of Ireland, 2016-07)Biopharmaceuticals are drugs which are primarily (glyco)protein in nature, that are produced in living cells using recombinant DNA technology – the combination of genetic material from multiple sources, creating sequences ... -
Analysis of bio-obtainable endocrine disrupting metals in river water and sediment, sewage influent/effluent, sludge, leachate, and concentrated leachate, in the Irish Midlands Shannon catchment.
(Hindawi, 2009-12)The application of an acid digestion and subsequent solid-phase extraction (SPE) procedure were implemented as preliminary treatments prior to quantifying the levels of potentially endocrine disrupting metals (EDMs) in a ... -
Prediction of toxigenic fungal growth in buildings by using a novel modelling system.
(American Society for Microbiology, 1999-11)There is growing concern about the adverse effects of fungal bioaerosols on the occupants of damp dwellings. Based on an extensive analysis of previously published data and on experiments carried out within this ...
